Pathology, Enzyme Activity and Immune Responses after Cryptocaryon irritans Infection of Golden Pompano Trachinotus ovatus (Linnaeus 1758)

Golden pompano (Trachinotus ovatus) has become an economically important fish in China the past decade. However, Cryptocaryon irritans, a parasitic ciliate, causes considerable economic losses mariculture of T. ovatus. To characterize pathogenesis C. irritans ovatus, pathological properties, immune-related enzyme activity and expression NEMO gene was analysed. The results from histological sections showed that there metamorphosis hyperplasia parasitized sites (skin) with leukocyte aggregation mucous cell increases after infection. Moreover, activities four enzymes, is, alkaline phosphatase (AKP), acid (ACP), superoxide dismutase (SOD) lysozyme (LZM), were significantly increased different tissues Furthermore, ORF ovatus NF-kappa-B essential modulator (ToNEMO) measures 1650 bp, encoding 548 amino acids. ToNEMO transcripts universally expressed all examined tissues, higher levels being observed immune-relevant central nervous tissues. mRNA infection gill, skin, liver, spleen head kidney. These suggested might be involved immune responses helped to elucidate physiological response fish.